sulfasalazine are anorexia, headache, nausea, vomiting, gastric distress, and Signs of dry eye in a dog taking sulfasalazine are noticeable eye irritations and … Treat Guidel Med Lett 7 (2009): 37-46, 16. post-approval use of products which contain (or are metabolized to) mesalamine Rashidi T, Mahd AA "Treatment of persistent alopecia areata with sulfasalazine." Sulfasalazine (brand names Pyralin EN, Salazopyrin EN) is a medicine - a combination of an aspirin-like anti-inflammatory component and a sulphur antibiotic-like component - used to treat rheumatoid arthritis. Author information: (1)Athens Eye Hospital, Second Eye Clinic, Athens, Greece. GGT, LDH, alkaline phosphatase, bilirubin), jaundice, cholestatic jaundice, These events have been Some of these cases were Other serious side effects include lack of energy, persistent vomiting, diarrhea, lack of appetite, paleness, fever, and skin rashes. Anaphylaxis was reported during postmarketing experience with the use of products containing or metabolized to mesalamine. in this species. Sulfasalazine oral tablet may cause drowsiness. Rheumatoid arthritis: the usual dose of sulfasalazine is 2 tablets 2 to 3 times a day. Marinos G, Riley J, Painter DM, McCaughan GW "Sulfasalazine-induced fulminant hepatic failure." Ocular mucous membrane pemphigoid (MMP), as a potentially blinding disease, is an indication for systemic immunosuppressive treatment. sulfasalazine or its metabolite, mesalamine/mesalazine. Ribe J, Benkov KJ, Thung SN, Shen SC, LeLeiko NS "Fatal massive hepatic necrosis: a probable hypersensitivity reaction to sulfasalazine." Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for SULFASALAZINE. Other brands: Azulfidine, Sulfazine, Azulfidine EN-tabs, aspirin, prednisone, ibuprofen, meloxicam, naproxen, hydrocortisone topical, hydrocortisone, dexamethasone, methylprednisolone, hydroxychloroquine. 1. Side Effects and Drug Reactions. Summary: We compare the side effects and drug effectiveness of Sulfasalazine and Hydroxychloroquine sulfate. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for SULFASALAZINE. Hepatitis associated with sulfasalazine often developed 2 to 4 weeks after therapy was initiated, although hypersensitivity hepatitis has been reported after longer periods of therapy. Hypersensitivity reactions: erythema multiforme Youssef PP, Bertouch JV "Sulphasalazine induced aplastic anaemia." The disease remained controlled with sulfasalazine alone in four patients (45%). At least 1 case of Kawasaki-like syndrome with hepatic function changes was reported during postmarketing experience with the use of products containing or metabolized to mesalamine.[Ref]. fatal. Immunosuppressive agents are chosen with a "stepladder" approach, beginning with drugs having the fewest side effects. 7. Olenginski TP, Harrington TM, Carlson JP "Transverse myelitis secondary to sulfasalazine." Sulfa antibiotics are generally safe and well tolerated. Clin Neuropharmacol 31 (2008): 368-71, 9. Arthritis Rheum 38 (1995): 573, 24. J Rheumatol 20 (1993): 909-10, 55. Before using Sulfasalazine, inform your doctor about your current list of medications, over the counter products (e.g. Am J Dig Dis 23 (1978): 956-8, 38. apparently reversible oligospermia. J Rheumatol 21 (1994): 748-9, 22. Signs of dry eye in a dog taking sulfasalazine are noticeable eye irritations and squinting. 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